![]() ![]() Keywords: nutrition status, osteoporotic vertebral fracture, percutaneous vertebroplasty, subsequent vertebral fractureĪs the population continues to age worldwide, the incidence rates of osteoporotic vertebral compression fracture (OVCF) appear to have been increasing. Health management and nutrition supplement after PVP is a potentially effective prevention strategy against SVF. The area under curve (AUC) for predicting SVF was 0.65 and 0.73 for the GNRI and 0.67 and 0.66 for the CONUT in men and women, respectively.Ĭonclusion: GNRI and CONUT are simple and effective tools for predicting SVF in patients undergoing PVP. Kaplan–Meier analysis showed that poor nutrition state was significantly associated with lower SVF-free survival (P< 0.05). Those with moderate–severe malnutrition also had a higher risk of SVF. ![]() Compared with normal nutrition, mild malnutrition was associated with higher risk for SVF (women: HR 2.37, p=0.001, men: HR 2.97, p=0.021 by GNRI women: HR 2.36, p=0.005, men: HR 3.62, p=0.002 by CONUT) after adjusting for confounding factors. Patients with SVF had lower BMI, serum albumin levels, GNRI scores, grip strength, lumbar BMD, and Short-Physical Performance Battery (SPPB) scores and higher fall rates and CONUT scores (P < 0.05). Results: During follow-up, 35 (25.4%) men and 85 (27.7%) women suffered SVF. Cox regression analysis was used to determine whether nutritional state was an independent predictor for SVF. Blood biochemical indexes, body mass index (BMI), bone mineral density (BMD), physical function, and muscle strength were measured at baseline. ![]() Methods: A total of 307 women and 138 men over 50 years old who underwent PVP for osteoporotic vertebral compression fracture (OVCF) were included. This study aimed to investigate the ability of the Controlling Nutritional Status (CONUT) and Geriatric Nutritional Risk Index (GNRI) to predict the incidence of subsequent vertebral fracture (SVF) after percutaneous vertebroplasty (PVP). ![]() Xin-Yue Fang, 1 Hao-Wei Xu, 1 Hao Chen, 1 Shu-Bao Zhang, 1 Yu-Yang Yi, 1 Xiao-Yong Ge, 1 Shan-Jin Wang 1– 3ġDepartment of Spinal Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China 2Institute of Spinal Diseases, Jinggangshan University, Jiangxi, People’s Republic of China 3Department of Orthopedic, Shanghai East Hospital, Ji’An Hospital, Jiangxi, People’s Republic of ChinaĬorrespondence: Shan-Jin Wang, Tel +86-21-3880455, Fax +86-21-63595958, Email īackground: The relationship between a poor nutritional state and the risk of fractures has not been investigated. ![]()
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